As part of the newly announced research collaboration, leadXpro will use its expertise in cryo-electron microscopy to help BASF in the structure-based research and discovery of new active ingredients.
According to leadXpro CEO Michael Henning, research supported by this type of technology is currently undergoing a “resolution revolution” by enabling visualization of viruses and membrane proteins at an unprecedented level of detail.
The Swiss scientist Jacques Dubochet and two German colleagues were awarded this year’s Nobel prize for chemistry for their work in developing cryo-electron microscopy.
“The collaboration agreement with leadXpro reflects the importance and value BASF places in developing strong research partnerships to discover new sustainable solutions for the challenges that farmers are facing globally,” said Harald Rang, Senior Vice President Global Research and Development Crop Protection at BASF, adding that the partnership will help create new active ingredients faster.
leadXpro is a spin-off of the Paul Scherrer Institute (PSI) in Villigen. The start-up is committed to the application of biophysical and structure-based methods for discovering next generation lead compounds for use in areas such as antibiotic resistance, treatment of serious neurological disorders or new approaches to the treatment of cancer.